Staging criteria for chronic renal failure

The criteria of chronic renal failure and the clinical severity of renal failure can be divided into 4 stages, that is, the renal function, the period of the nitrogen, the renal failure and uremia. The early symptoms of chronic renal failure, the following is the specific introduction of chronic renal failure stage:
One stage: renal function:
Glomerular filtration rate was reduced to 30-60 ml / min, while the glomerular filtration rate was 120 liters per minute. The nephron reduction of about 20-25 per cent. Renal reserve capacity although has lost, but for the excretion of the metabolites, regulation of water, electrolyte and acid-base balance ability is good, so clinical no special performance, serum muscle enzymes and blood urea nitrogen (BUN) usually normal or sometimes slightly elevated.
The two stage: the stage of the disease:
Chronic renal failure staging criteria for the reduction of glomerular filtration rate to 25 ml / min, the renal units decreased 50%-70%, renal dysfunction, the emergence of night urine or urine, varying degrees of anemia, often with nitrogen, blood creatinine, urea nitrogen increased. Clinical can have fatigue, loss of appetite, nausea and mild discomfort, etc.. This period, such as the neglect of renal function protection or additional load, will appear serious vomiting, diarrhea, blood deficiency, if there is infection or use of the use of renal toxicity drugs, can cause renal function rapidly decline and failure.
Three stage: renal failure stage (early stage):
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The glomerular filtration rate decreased to 10-15 ml per minute, and the renal units decreased about 70%-90%, the renal function was severely damaged, and it could not maintain the metabolism and water electrolyte and acid-base balance in the body. It is not possible to maintain the stability of the machine body, so that blood creatinine, urea nitrogen were significantly increased, urine concentration and dilution dysfunction, acid poisoning, water sodium retention, low calcium, high phosphorus, potassium and other balance disorders. Can have obvious anemia and gastrointestinal symptoms, such as nausea, vomiting, loss of appetite. Also can have the neuropsychiatric symptoms, such as fatigue, inattention, depression etc..
Phase four: Uremia
Glomerular filtration rate decreased to 10 ml per minute -15 ml of the following renal units decreased by more than 90%, this period is chronic renal failure, the clinical symptoms of renal failure is more obvious, the performance of systemic multiple organ failure, such as gastrointestinal, nervous system, cardiovascular system, blood system, respiratory system, skin and metabolic system. The clinical performance for nausea, vomiting, irritability uneasiness, increased blood pressure, palpitation, chest tightness, not lying, dyspnea, severe anemia, convulsion, and in serious cases, coma, hyperkalemia, hyponatremia, low calcium, high phosphorus acidemia. This period needs to rely on dialysis to sustain life. Often due to hyperkalemia, cerebral edema, pulmonary edema, heart failure and sudden death.

Through the "chronic renal failure staging criteria" to explain, the experts warm prompt you patients, in the treatment of patients with chronic renal failure can be cured, to maintain a good state of mind, the family should always pay attention to the development of the patient's condition. The good state of mind and the family's care for the patient is equally important.